2017年8月4日星期五

The clinical manifestation of polycystic kidney disease

Depending on the size of the cyst, the degree of renal tissue compression, as well as the availability of complications, etc., infant type often associated with other deformities, mostly in the weeks after birth, died. Adult clinical symptoms are:

1 waist, abdomen discomfort or pain as the most common symptoms, mostly in the pain, dull pain, fixed on one or both sides, can be radiated to the lower back or lower abdomen. The reason is due to swelling in the kidney dilatation of the kidney capsule or traction of the renal pedicle or oppression caused by adjacent organs, sudden pain exacerbations often caused by intracapsular hemorrhage or secondary infection. About 1/5 of the patient's pain was renal colic-like, mostly due to the merger of stones or hemorrhage after clotting caused by urinary tract.

2 hematuria: accounting for 25 to 50%. Can be expressed as microscopic hematuria or gross hematuria, often in the trauma, severe labor or infection induced or aggravated, hematuria often cyclical, interval up to several months or years, a large number of hematuria in addition to causing renal colic, sometimes caused Urinary tract obstruction, hematuria mainly due to the wall of the blood vessels were excessive pull caused by rupture.

3 proteinuria, accounting for about 70 to 90% of the general amount of small, 24 hours in the following 2 grams, occasionally more than 10 grams, it does not produce nephrotic syndrome.

4 Hypertension group, accounting for about 70 ~ 75%. High blood pressure caused by headaches, dizziness and other symptoms, continued to rise in blood pressure caused by cardiac enlargement, and finally the development of heart failure.

5 abdominal mass, both sides can be touched accounted for 50 to 80% of the unilateral touch accounted for 15 to 30% of the general texture of the more rigid, with breathing and exercise. Individuals may be fixed by adhesion.

6 infection, 50 ~ 70% combined with renal infection, severe cases can cause renal suppurative, acute infection or suppuration, the performance of chills, fever, urinary frequency, pyuria, about 1/3 of patients behave like chronic pyelonephritis, Due to great cysts oppression, can cause hydronephrosis.

7 kidney stones, accounting for about 10%, manifested as renal colic.

8 uremia, due to cystic oppression, complicated by pyelonephritis and other causes of renal parenchyma caused by uremia.
9 combined with other developmental malformations, polycystic liver and intracranial aneurysm more common, in addition can still merge the spleen, pancreas, ovary, or vice testis and other cysts.

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